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Chinese Researchers Correct Genetic Mutation In Embryos Using Base Editing

来源于:Slashdot
dryriver writes: Chinese researchers have taken tissue from a beta-thallasemia patient, created cloned embryos from that patient's cells, and used a genetic editing technique known as Base Editing to correct the gene mutation that causes beta-thallasemia. The embryos were not implanted in a womb, so no actual babies were created during the procedure. The BBC reports: "Precise 'chemical surgery' has been performed on human embryos to remove disease in a world first, Chinese researchers have told the BBC. The team at Sun Yat-sen University used a technique called base editing to correct a single error out of the three billion 'letters' of our genetic code. They altered lab-made embryos to remove the disease beta-thalassemia. The embryos were not implanted. The team says the approach may one day treat a range of inherited diseases. Base editing alters the fundamental building blocks of DNA: the four bases adenine, cytosine, guanine and thymine. Base editing works on the DNA bases themselv 查看全文>>